Targeting cathepsin G in myeloid leukemia
نویسنده
چکیده
Cathepsin G (CG) is a serine protease normally found within the azurophil granules of neutrophils. CG is expressed during the early stages of normal myeloid differentiation and-aberrantly-by myeloid leukemia cells. We have recently identified CG-derived HLA-A*0201-binding peptides that constitute promising targets for the immunotherapy of myeloid leukemia.
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عنوان ژورنال:
دوره 2 شماره
صفحات -
تاریخ انتشار 2013